Dr Mercola Complete Spore Restore

By now, you probably know that probiotics are beneficial for you, but you may not be aware of sporebiotics, and how they can benefit a wide variety of health problems, including autism and other neurological and immune-related diseases. Dr. Dietrich Klinghardt, a long-time mentor of mine, is both an M.D. and a Ph.D.

While trained in Germany, his practice is based in Seattle, where he sees some of the sickest patients around. Obviously, if you want good health, you need to clean up your diet. We won't go into that here. Instead, we'll focus on spore-based probiotics, which are an excellent complement to regular probiotics. What Are Spore-Based Probiotics?

Spore-based probiotics are part of a group of derivatives of the microbe called bacillus. This genus has hundreds of subspecies, the most important of which is bacillus subtilis. Essentially, spore-based probiotics consist of the cell wall of bacillus spores. The first product of this kind came out in Germany in 1935 and was created by Gunther Enderlein, a German microbiologist.

Contrary to popular belief, the human body actually has the ability to produce its own vitamin C. This is done by a specific species of gut microbes — the bacillus — which converts sugar into vitamin C. It's also involved in producing vitamin K, which works synergistically with Vitamin D.

"[T]hat was a revolution for me when I found this out," Klinghardt says. "Other species then have the function of creating amino acids. In fact, there is a famous Swiss researcher, Bircher-Benner, who invented muesli … Bircher-Benner was a wonderful researcher, a medical doctor who, in the 1940s, went across different parts of the world to see how long people lived and what they ate.

He found a subculture in the Caribbean where people lived well into the hundreds, but they only ate one food. It was sweet potatoes. He thought 'How do this people survive on sweet potatoes?' Because there are no amino acids in it, no fatty acids. There's hardly any vitamins in it.

What he found is that these inhabitants had a species of clostridium in their gut. They were actually producing the whole spectrum of the essential amino acids and the whole spectrum of essential fatty acids [in their guts]."

Spore-Based Probiotics Are a Primary Tool to Boost Immune Tolerance

There are at least 2,500 species of microbes living in your gut and most, if not all of them, serve your body in a symbiotic way. They either produce something you need, metabolize toxic products so they can be safely eliminated or help reset or balance your immune system and immune tolerance, which goes deeper than fighting inflammation. As noted by Klinghardt:

"Many of us have lost our tolerance towards the factors that are in our environment. Many patients have lost the tolerance toward food that would serve them in many ways, but they cannot tolerate it. The truth is that the healthier a person is today, the more immune tolerant that person is. That means, they're the ones that are not affected greatly by the electromagnetic environment.

They're the people that avoid the chemicals that are in the air and in the food — the aluminum in the air, the glyphosate in the food. The question was always, 'Is immune tolerance a consequence of good health?' Or 'Is immune tolerance actually the factor that makes people healthy?' I would postulate the latter.

So, the bacillus spores … dramatically increase our immune tolerance. With that it becomes not just one of the many things you can do for health, not one of the many other things you can try or put in your program, but it becomes a very primary issue. We have very few tools to predictively increase immune tolerance in a patient and the spores are right now No. 1."

Spore-Based probiotics Are Ideal If You're on Antibiotics

As mentioned, these spore-based probiotics do not contain any live bacillus strains, only its spores — the protective shell around the DNA and the working mechanism of that DNA. As a consequence of this, they are unaffected by antibiotics. Many are overexposed to antibiotics, if not through medicine then through our food (as 80 percent of the antibiotics sold in the U.S. are used in food production).

Antibiotics, of course, indiscriminately kill bacteria, both good and bad. This is why secondary infections and lowered immune function are common side effects of antibiotics. Chronic low-dose exposure through food also takes a toll on your gut microbiome which can result in chronic ill health, not to mention the fact that chronic exposure raises the risk of drug resistance.

The beautiful thing about spore probiotics is that they can more effectively help reestablish your gut microbiome since they're not being destroyed by antibiotics. Moreover, most acidophilus products have the drawback of not being able to survive the passage through your stomach acid if you take them on an empty stomach, which most people do. Poor-quality probiotics may not even be alive by the time you take them.

The Importance of Healthy Biofilm

If you take your probiotics after a meal, your stomach's pH will be slightly elevated, allowing some to survive, but you're still unlikely to get even 25 percent of the stated units of the product.

"For [probiotics] to become active and actually work for you, they have to germinate. That's number one. They start to germinate in the small intestine, and then they have to establish residency. That means they have to actually talk to the other microbes and be accepted by them. The other species basically have to welcome them and have to agree to a certain number of them so they can establish themselves there.

Because the bacillus species is a regular innate inhabitant of our normal bowel flora, the spores, once they [germinate], are fully accepted into the community of our resident gut microbiome, and unfold the property of their symbiotic contribution in the gut that way … [T]he research is very clear that the spores, when they … germinate, establish permanent residency for their lifespan, and start replicating in the gut …

By the way, the bacillus spores tend to also be very actively involved in creating healthy biofilm, and I think this is important for people to know, because biofilm has gotten such a bad rep recently. All our resident microbes have a blueprint of themselves and leave a germinating layer in healthy biofilm, which lines the entire gut … [P]athogenic biofilm is a whole different animal, but we have to be careful with the insane strategies to destroy all biofilm.

Healthy gut microbes have a blueprint of themselves lining the entire gut in biofilm, and the bacillus is very involved in creating healthy biofilm. The biofilm is [like] a nursery for the [microbes] we need to help break down our food, metabolize it, talk to the immune system, creating immune tolerance and all that."

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